Table 1. Patient characteristics and clinical conditions

Characteristics Overall1) (n=170, %) Thrombocytopenia1) p-value
No (n=110, %) Yes (n=60, %)
Demographic
 Age (year) 69.5 (59.0, 79.8) 68.0 (59.0, 75.8) 74.0 (59.5, 85.2) 0.061
 Sex, male 104 (61.2) 66 (60.0) 38 (63.3) 0.794
 Height (cm) 160 (156, 165) 160 (156, 165) 160 (157, 167) 0.801
 Weight (kg) 57.0 (50.0, 65.8) 57.0 (50.0, 65.0) 57.8 (49.5, 67.2) 0.962
 Body mass index (kg/m2) 22.3 (19.5, 25.2) 22.2 (19.4, 25.3) 22.7 (19.7, 24.8) 0.990
Clinical conditions
 Charlson comorbidity index 2.0 (1.0, 3.0) 2.0 (1.0, 3.0) 3.0 (1.0, 3.3) 0.075
 eGFR (CKD-EPI)2) (mL/min per 1.73 m2) 74.0 (45.3, 96.3) 78.0 (55.2, 99.8) 63.0 (40.5, 88.2) 0.022
 eGFR (CKD-EPI)<60 mL/min per 1.73 m2 63 (37.1) 33 (30.0) 30 (50.0) 0.016
 Length of stay (days) 15.25 (11.0, 22.0) 14.0 (10.0, 18.0) 19.8 (15.0, 29.2) <0.001
Outcome
 Cured/improved Worsen 165 (97.1) 5 (2.9) 109 (99.1) 1 (0.9) 56 (93.3) 4 (66.7) 0.071
Type of infection
 Skin and soft tissue infection 66 (38.8) 46 (41.8) 20 (33.3) NA
 Bacteremia 18 (10.6) 14 (12.7) 4 (6.7)
 Bone and joint infection 18 (10.6) 8 (7.3) 10 (16.7)
 Community-acquired pneumonia 50 (29.4) 30 (27.3) 20 (33.3)
 Central nervous system infection 3 (1.8) 2 (1.8) 1 (1.7)
 Hospital-acquired pneumonia 16 (9.4) 10 (9.1) 6 (10.0)
 Others 14 (8.2) 9 (8.2) 5 (8.3)
Laboratory
 Serum creatinine (mg/dL) 0.94 (0.71, 1.29) 0.89 (0.68, 1.26) 0.98 (0.76, 1.52) 0.038
 Total bilirubin (mg/dL) 10.4 (8.1, 15.0) 10.6 (8.1, 13.6) 10.8 (8.1, 15.0) 0.682
 Total bilirubin≥20.5 umol/L 12 (7.1) 6 (5.5) 6 (10.0) 0.349
 Aspartate aminotransferase (U/L) 29.0 (22.0, 48.0) 28.0 (21.0, 51.0) 32.0 (23.0, 49.0) 0.304
 Alanine aminotransferase (U/L) 24.0 (14.0, 41.8) 25.0 (15.0, 46.0) 24.5 (14.0, 45.5) 0.555
 Albumin (g/L) 30.2 (5.2) 30.6 (5.3) 29.3 (4.8) 0.105
 Hemoglobin (g/dL) 107.5 (93.0, 121.8) 110 (93, 125) 106 (94, 118) 0.395
 Baseline platelet count (103 cells/µL) 278.5 (210.3, 349.5) 264 (183, 330) 326 (243, 407) 0.001
 Baseline platelet count<150×103 cells/µL 10 (5.9) 8 (7.3) 2 (3.3) 0.497
Data are presented as n (%), mean (standard deviation), or median (interquartile range).
Estimated glomerular filtration rate using Chronic Kidney Disease Epidemiology Collaboration equation (eGFR CKD-EPI).
eGFR, estimated glomerular filtration rate; CKD-EPI, chronic kidney disease epidemiology collaboration; NA, not applicable.