Table 2. Classification of plant species based on the in vitro PBMCs proliferation using MTT assay

Classification based on ethanol extract bioactivity Plant species IC50 (or EC50) (μg/ml) of the most potential fraction
Stimulate the in vitro PBMCs proliferation Glycyrrhiza glabra L EC50(CHCl3)=10
Astragalus membranaceus EC50(CHCl3)=50
Inhibit the in vitro PBMCs proliferation Cassia alata L. IC50(CHCl3)=16.21
Wedelia chinensis IC50(CHCl3)=16.12
Lonicera japonica IC50(CHCl3)=142.3
Caesalpinia sappan L. IC50(EA)=36.52
Schefflera heptaphylla IC50(CHCl3)=34.99
Piper betle IC50(CHCl3)=27.81
No effect on the in vitro PBMCs proliferation Cassia tora L -
Coscinium fenestratum -
Angelica sinensis -
Achyranthes aspera L -
Camellia sinensis -