Table 2. IC
50
and Docking Scores of 14 structures and Ortistat
Structure
IC
50
(μM)
Docking Score (kcal/mol)
Orlistat
2.3
-6.9
T76
111.08
-8.6
T101
>120
-9.0
T96
94.97
-9.1
T97
50.51
-9.1
T48
107.41
-9.1
T99
76.18
-9.4
T102
>120
-9.4
T78
>120
-9.5
T45
109.98
-9.6
T100
100.64
-9.6
T42
>120
-9.7
T43
87.70
-9.9
T95
57.89
-10.1
T98
113.34
-10.1